Ethylenediamine → HCID 10702373、化合物
反応式
CO[C:3](=[O:20])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[C:10](=O)C1C=CC(OC)=CC=1.[CH2:21]([NH2:24])[CH2:22][NH2:23]>>[NH:23]1[CH:10]2[C:5]3[C:4]([C:3](=[O:20])[N:24]2[CH2:21][CH2:22]1)=[CH:9][CH:8]=[CH:7][CH:6]=3参加物
3
実験手順
Condense methyl-o-(p-methoxybenzoyl)benzoate (7 g.) and ethylenediamine (8 ml.) by procedure of Example 1 to obtain 9b-p-methoxyphenyl)-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one, m.p. 159° C. (elemental analysis confirms the empirical formula C17H16N2O2), reduce with lithium aluminum hydride, and treat with hydrogen chloride as described in Example 1 to obtain 1,2,3,4,5,6-hexahydro-1-(p-methoxyphenyl)-2,5-benzodiazocine dihydrochloride, m.p. 260° C.
出典と根拠
- ORDレコード
- ord-774c4d604b694564baff65098b8071a3
- 出典データセット
- uspto-grants-1976_11
- 特許番号
- US03994920
反応ノート
読み込み中…