Acetaldehyde → 1-(hydroxymethyl)-9,10-dimethoxy-1,6,7,11b-tetrahydro-2H,4H-[1,3]oxazino[4,3-a]isoquinoline
反応式
[OH:1][CH2:2][CH:3]([CH2:18][OH:19])[CH:4]1[C:13]2[C:8](=[CH:9][C:10]([O:16][CH3:17])=[C:11]([O:14][CH3:15])[CH:12]=2)[CH2:7][CH2:6][NH:5]1.[CH:20](=O)C>C(O)C>[OH:1][CH2:2][CH:3]1[CH:4]2[C:13]3[C:8]([CH2:7][CH2:6][N:5]2[CH2:20][O:19][CH2:18]1)=[CH:9][C:10]([O:16][CH3:17])=[C:11]([O:14][CH3:15])[CH:12]=3参加物
4
実験手順
0.01 mole (2.67 g) of 1-[bis(hydroxymethyl)-methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline is dissolved in 30 ml of ethanol, and the solution is stirred with 0.015 mole of acetaldehyde for one hour. The reaction mixture is evaporated to dryness to yield the aimed compound in a crystalline form.
後処理
- customThe reaction mixture is evaporated to dryness
出典と根拠
- ORDレコード
- ord-59e0faa972a344aa8343910e46e58372
- 出典データセット
- uspto-grants-1986_11
- 特許番号
- US04623647
反応ノート
読み込み中…