Hydrochloric Acid → HCID 178487304、化合物
反応式
C[O:2][C:3]1[C:4]2[N:5]([CH:15]=[N:16][N:17]=2)[C:6]2[C:11]([N:12]=1)=[CH:10][C:9]([O:13][CH3:14])=[CH:8][CH:7]=2.Cl>C(O)(=O)C>[OH:2][C:3]1[C:4]2[N:5]([CH:15]=[N:16][N:17]=2)[C:6]2[C:11]([N:12]=1)=[CH:10][C:9]([O:13][CH3:14])=[CH:8][CH:7]=2参加物
4
実験手順
A mixture consisting of 1.6 g. (0.0069 mole) of 4,7-dimethoxy-[1,2,4]triazolo[4,3-a]quinoxaline, 16 ml. of 1N hydrochloric acid and 48 ml. of glacial acetic acid was refluxed for a period of three hours. Upon completion of this step, the reaction mixture was poured over ice and filtered. The recovered product was then collected on the filter funnel and washed with diethyl ether to ultimately afford 1.19 g. (80%) of pure 4-hydroxy-7-methoxy[1,2,4]triazolo[4,3-a]quinoxaline, m.p. >250° C.
後処理
- additionUpon completion of this step, the reaction mixture was poured over ice
- filtrationfiltered
- customThe recovered product was then collected on the filter funnel
- washwashed with diethyl ether to ultimately afford 1.19 g
出典と根拠
- ORDレコード
- ord-e160ce800f004eeebc04a0da2f78ff2e
- 出典データセット
- uspto-grants-1986_11
- 特許番号
- US04623725
反応ノート
読み込み中…