Ethanol → Ethyl [2,3-dichloro-4-(6-ethyl-3-oxo-1-cyclohexen-1-yl)-phenoxy]acetate

HRID 1732178ノート

反応式

HRID 1732178 の反応式
[Cl:1][C:2]1[C:12]([Cl:13])=[C:11]([C:14]2[CH:19]([CH2:20][CH3:21])[CH2:18][CH2:17][C:16](=[O:22])[CH:15]=2)[CH:10]=[CH:9][C:3]=1[O:4][CH2:5][C:6]([OH:8])=[O:7].[CH2:23](O)[CH3:24]>S(=O)(=O)(O)O>[Cl:1][C:2]1[C:12]([Cl:13])=[C:11]([C:14]2[CH:19]([CH2:20][CH3:21])[CH2:18][CH2:17][C:16](=[O:22])[CH:15]=2)[CH:10]=[CH:9][C:3]=1[O:4][CH2:5][C:6]([O:8][CH2:23][CH3:24])=[O:7]

参加物

4

反応物 2

HCID 702EthanolHCID 10759778[2,3-Dichloro-4-(6-ethyl-3-oxo-1-cyclohexen-1-yl)phenoxy]acetic acid

生成物 1

HCID 13749111Ethyl [2,3-dichloro-4-(6-ethyl-3-oxo-1-cyclohexen-1-yl)-phenoxy]acetate

試薬・触媒・溶媒 1

HCID 1118Sulfuric Acid触媒

実験手順

A stirred solution of [2,3-dichloro-4-(6-ethyl-3-oxo-1-cyclohexen-1-yl)phenoxy]acetic acid (3.43 g, 0.01 mole) in ethanol (50 ml) containing sulfuric acid (4 drops) was heated at reflux for 4 hours. The ethanol was evaporated at reduced pressure, the residue dissolved in ether, washed with dilute sodium hydroxide, water, dried over magnesium sulfate and evaporated in vacuo to give 3.31 g of ethyl [2,3-dichloro-4-(6-ethyl-3-oxo-1-cyclohexen-1-yl)-phenoxy]acetate which melted at 110°-112° C.

後処理

  1. temperaturewas heated
  2. temperatureat reflux for 4 hours
  3. customThe ethanol was evaporated at reduced pressure
  4. dissolutionthe residue dissolved in ether
  5. washwashed with dilute sodium hydroxide, water
  6. dry with materialdried over magnesium sulfate
  7. customevaporated in vacuo

出典と根拠

ORDレコード
ord-27a63db16c5442c7a29ebdb35af297ee
出典データセット
uspto-grants-1986_11
特許番号
US04625047

反応ノート

読み込み中…