Potassium Hydroxide → HCID 54394348、化合物

HRID 1732467ノート

反応式

HRID 1732467 の反応式
[CH3:1][O:2][C:3]([NH:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([S:14][C:15]3[CH:20]=[CH:19][C:18]([O:21]C(=O)C)=[CH:17][CH:16]=3)=[CH:10][N:9]2[CH:25]=1)=[O:4].[OH-].[K+]>CO.O>[CH3:1][O:2][C:3]([NH:5][C:6]1[N:7]=[C:8]2[CH:13]=[CH:12][C:11]([S:14][C:15]3[CH:20]=[CH:19][C:18]([OH:21])=[CH:17][CH:16]=3)=[CH:10][N:9]2[CH:25]=1)=[O:4]

参加物

4

反応物 2

HCID 14797Potassium HydroxideHCID 53698142HCID 53698142、化合物

生成物 1

HCID 54394348HCID 54394348、化合物

試薬・触媒・溶媒 1

HCID 22242641Methanol--water (1/1)溶媒

実験手順

1.0 Gm. of the acetate derivative obtained in Example 15 is heated with a 10 ml. 50% methanol-water solution of 0.5 g. of potassium hydroxide for one hour. After evaporation of the methanol in vacuo the reaction mixture is acidified with glacial acetic acid. The resultant solids are removed by filtration, washed with water and dried to yield 2-(methoxycarbonylamino) 6-(p-hydroxyphenylthio) imidazo [1,2-a] pyridine.

後処理

  1. customAfter evaporation of the methanol in vacuo the reaction mixture
  2. customThe resultant solids are removed by filtration
  3. washwashed with water
  4. customdried

出典と根拠

ORDレコード
ord-b92df12d43be428594532fe30a7dd20a
出典データセット
uspto-grants-1980_12
特許番号
US04237300

反応ノート

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