化工社化工社 化学情報印刷レポート · 研究参考用
Ethyl Bromide → N-Ethyl-N-methyl-2-thiophene methanamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl Bromide | HCID 6332 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | N-Methyl-1-(thiophen-2-yl)methanamine | HCID 436153 | — |
| 溶媒 | Water | HCID 962 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 溶媒 | Sodium Bicarbonate | HCID 516892 | — |
| 生成物 | N-Ethyl-N-methyl-2-thiophene methanamine | HCID 12788071 | — |
反応手順
Bromoethane (150 ml), triethylamine (7.3 ml) and N-methyl-2-thiophenemethanamine (21.2 g) were stirred at room temperature in toluene (212 ml) for 4 days. The solution was diluted with water, saturated with sodium bicarbonate and extracted with ethyl acetate. The organic extracts were distilled to give the title compound as an oil (13.6 g) b.p. 46° (16 mm).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04239769 |
| 出典データセット | uspto-grants-1980_12 |
| ORD ID | ord-2cc545f257c747f1846a3e4260f3340f |
| 出典メモ | uspto-grants-1980_12 |