3-Methoxy-dihydrothiophene-4-carboxylic acid methyl ester → Methyl 4-methoxythiophene-3-carboxylate
反応式
ClCl.C(Cl)(Cl)(Cl)Cl.[CH3:8][O:9][C:10]([C:12]1[CH:13]([O:17][CH3:18])[CH2:14][S:15][CH:16]=1)=[O:11]>C(Cl)(Cl)(Cl)Cl>[CH3:8][O:9][C:10]([C:12]1[C:13]([O:17][CH3:18])=[CH:14][S:15][CH:16]=1)=[O:11]参加物
4
実験手順
15 Parts by volume of a Cl2 /CCl4 solution (7.1 parts of chlorine in 100 parts of CCl4) are added in the course of 10 minutes to a solution, cooled to 0° C., of 1.74 parts of 3-methoxy-dihydrothiophene-4-carboxylic acid methyl ester in 15 parts by volume of CCl4. The mixture is kept at 0° C. for one hour. The end product is isolated from the reaction mixture by the method described in Example 1c. 1.6 parts (93% of theory) of 3-methoxythiophene-4-carboxylic acid methyl ester of melting point 66°-67° C. are obtained.
後処理
- customThe end product is isolated from the reaction mixture by the method
出典と根拠
- ORDレコード
- ord-586ff7b72a144bea98ea1afc17e8b01b
- 出典データセット
- uspto-grants-1980_12
- 特許番号
- US04239897
反応ノート
読み込み中…