Hydrochloric Acid → 3-(4'-Fluoro-4-biphenylyl)butylamine, hydrochloride
反応式
C1(=O)[N:5]([CH2:6][CH2:7][CH:8]([C:10]2[CH:15]=[CH:14][C:13]([C:16]3[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=3)=[CH:12][CH:11]=2)[CH3:9])C(=O)C2=CC=CC=C12.[ClH:29]>>[ClH:29].[F:22][C:19]1[CH:18]=[CH:17][C:16]([C:13]2[CH:14]=[CH:15][C:10]([CH:8]([CH3:9])[CH2:7][CH2:6][NH2:5])=[CH:11][CH:12]=2)=[CH:21][CH:20]=1参加物
3
実験手順
37.3 g of 1-phthalimido-3-(4'-fluoro-4-biphenylyl)butane are boiled for 6 hours with 400 ml of 20% aqueous hydrochloric acid, evaporated and worked up using sodium hydroxide solution and ether to give 3-(4'-fluoro-4-biphenylyl)butylamine, hydrochloride, m.p. 222°-224°.
後処理
- customevaporated
出典と根拠
- ORDレコード
- ord-2608ab0b49d742eb968b25e2e0900b6c
- 出典データセット
- uspto-grants-1980_12
- 特許番号
- US04239759
反応ノート
読み込み中…