1alpha-Methyl-4-androstene-17beta,19-diol dipropionate → 4-Methyl-4-androstene-17beta,19-diol dipropionate

反応式

[CH3:1]C1CCC[C@@]2(CO)C=1CC[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC[C@@H]2O.[C:23]([O:27][C@H:28]1[CH2:33][CH2:32][C@H:31]2[C@H:34]3[C@H:49]([CH2:50][CH2:51][C@:29]12[CH3:30])[C@:42]1([CH2:43][O:44][C:45](=[O:48])[CH2:46][CH3:47])[C:37](=[CH:38][CH2:39][CH2:40][C@@H:41]1C)[CH2:36][CH2:35]3)(=[O:26])[CH2:24][CH3:25]>>[C:23]([O:27][C@H:28]1[CH2:33][CH2:32][C@H:31]2[C@H:34]3[C@H:49]([CH2:50][CH2:51][C@:29]12[CH3:30])[C@:42]1([CH2:43][O:44][C:45](=[O:48])[CH2:46][CH3:47])[C:37](=[C:38]([CH3:1])[CH2:39][CH2:40][CH2:41]1)[CH2:36][CH2:35]3)(=[O:26])[CH2:24][CH3:25]

参加物

反応物 2

HCID 705838891alpha-Methyl-4-androstene-17beta,19-diol dipropionate

HCID 705848084-Methyl-4-androsten-17beta,19-diol

生成物 1

HCID 705849144-Methyl-4-androstene-17beta,19-diol dipropionate

実験手順

Substituting 1α,17α-dimethyl-4-androstene-17β,19-diol and 4-methyl-4-androstene-17β,19-diol for the 1α-methyl-4-androstene-17β,19-diol above results in the preparation of 1α,17α-dimethyl-4-androstene-17β,19-diol dipropionate and 4-methyl-4-androstene-17β,19-diol dipropionate.

出典と根拠

ORDレコード: ord-234260e5bbef42c8a5a55108be6b63dc
出典データセット: uspto-grants-1980_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04239681

反応ノート

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