HCID 54200145、化合物 → HCID 54282494、化合物
反応式
C([S:4][CH:5]([C:16]([F:19])([F:18])[F:17])[C:6]([N:8]1[CH2:15][CH2:14][CH2:13][C@H:9]1[C:10]([OH:12])=[O:11])=[O:7])(=O)C>O.N>[SH:4][CH:5]([C:16]([F:19])([F:17])[F:18])[C:6]([N:8]1[CH2:15][CH2:14][CH2:13][C@H:9]1[C:10]([OH:12])=[O:11])=[O:7]参加物
4
実験手順
1-(2-Acetylthio-3,3,3-trifluoropropanoyl)-L-proline (4 g.) is dissolved in a mixture of water (8 ml.) and concentrated ammonia (8 ml.) under a blanket of nitrogen. After thirty minutes at room temperature, the reaction mixture is acidified and extracted with ethyl acetate. The organic phase is dried over magnesium sulfate and concentrated to dryness in vacuo to yield 1-(2-mercapto-3,3,3-trifluoropropanoyl)-L-proline.
後処理
- waitAfter thirty minutes at room temperature
- extractionextracted with ethyl acetate
- dry with materialThe organic phase is dried over magnesium sulfate
- concentrationconcentrated to dryness in vacuo
出典と根拠
- ORDレコード
- ord-3bd01a04bc974cb69a4f6b647aa0c1c6
- 出典データセット
- uspto-grants-1980_12
- 特許番号
- US04241076
反応ノート
読み込み中…