Sulfuryl chloride → HCID 12593650、化合物

HRID 1733587ノート

反応式

HRID 1733587 の反応式
[Cl:1][C:2]1[CH:15]=[CH:14][CH:13]=[C:12]([Cl:16])[C:3]=1[NH:4][CH:5]1[C:9]([C:10]#[N:11])=[CH:8][S:7][CH2:6]1.S(Cl)(Cl)(=O)=O>C(Cl)Cl>[Cl:1][C:2]1[CH:15]=[CH:14][CH:13]=[C:12]([Cl:16])[C:3]=1[NH:4][C:5]1[C:9]([C:10]#[N:11])=[CH:8][S:7][CH:6]=1

参加物

4

反応物 2

HCID 24648Sulfuryl chlorideHCID 20300151HCID 20300151、化合物

生成物 1

HCID 12593650HCID 12593650、化合物収率 75%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒2 回

実験手順

A solution of 0.27 part of 3-(2',6'-dichloro-anilino)-4-cyanodihydrothiophene in 15 parts by volume of dry methylene chloride is added, in the course of 30 minutes, to a solution of 0.12 part by volume of sulfuryl chloride in 15 parts by volume of dry methylene chloride at 0° C. The end product is isolated from the reaction mixture by the method described in Example 1c. 0.20 (75% of theory) of 3-(2',6'-dichloroanilino)-4-cyanothiophene of melting point 105°-108° C. are obtained.

後処理

  1. customThe end product is isolated from the reaction mixture by the method

出典と根拠

ORDレコード
ord-fb384d0a976445c5ae0a0d26994785d4
出典データセット
uspto-grants-1980_12
特許番号
US04242518

反応ノート

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