HCID 43218479、化合物 → HCID 20300160、化合物
反応式
CO[C:3](=[O:16])[CH2:4][CH2:5][S:6][CH2:7][C:8](=[O:15])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.O(C)[Na].CO>>[OH:16][CH:3]1[CH:4]=[CH:5][S:6][CH:7]1[C:8](=[O:15])[C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1参加物
3
反応条件
- 温度
- 0 °C
実験手順
23.8 parts of 3-(benzoylmethylthio)-propionic acid methyl ester are added in the course of 30 minutes to 36 parts of a 30 percent strength by weight NaOCH3 /MeOH solution which has been cooled to 0° C., and the mixture is stirred for 2 hours at from 0° to 10° C. The end product is isolated from the reaction mixture by the method described in Example 14(b). 18.5 parts (90% of theory) of 3-hydroxy-2-benzoyldihydrothiophene of boiling point 137°-140° C./0.16-0.08 mbar are obtained.
後処理
- customThe end product is isolated from the reaction mixture by the method
出典と根拠
- ORDレコード
- ord-57520a8b14f74a42963d9f0dc8347447
- 出典データセット
- uspto-grants-1980_12
- 特許番号
- US04242518
反応ノート
読み込み中…