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HRID 1735536作成日:2026年10月26日

2-(Thiophen-2-yl)propan-2-amine → N-[1-Methyl-1-(2-thienyl)ethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamide

https://huagongshe.com/reaction/1735536

反応式

関与物質

役割名称HCID仕込み量
反応物2-(Thiophen-2-yl)propan-2-amineHCID 45099—
反応物S-2pyridyl 3-cyanoandrosta-3,5-diene-17beta-thiocarboxylateHCID 15380265—
生成物N-[1-Methyl-1-(2-thienyl)ethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamideHCID 2286241888%

反応手順

Following a procedure similar to that described in Example 3(b), but using S-2-pyridyl 3-cyanoandrosta-3,5-diene-17β-thiocarboxylate [prepared as described in Example 3(a)] and 1-methyl-1-(2-thienyl)ethylamine (prepared as described in Preparation 11a) as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a yield of 88%.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05536714
出典データセットuspto-grants-1996_07
ORD IDord-66e178d4320d4995982374d427299c92
出典メモuspto-grants-1996_07