(4-Phenyl-1H-imidazol-5-yl)methanol → HCID 19973549、化合物

HRID 1736484ノート

反応式

HRID 1736484 の反応式
[C:1]1([C:7]2[N:8]=[CH:9][NH:10][C:11]=2[CH2:12][OH:13])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>[O-2].[O-2].[Mn+4].O1CCOCC1>[C:1]1([C:7]2[N:8]=[CH:9][NH:10][C:11]=2[CH:12]=[O:13])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

4

反応物 1

HCID 20253759(4-Phenyl-1H-imidazol-5-yl)methanol

生成物 1

HCID 19973549HCID 19973549、化合物収率 70.8%

試薬・触媒・溶媒 2

HCID 178418406HCID 178418406、化合物触媒HCID 312751,4-Dioxane溶媒

実験手順

1,4-Dioxane (10 ml) was mixed with 1 g of (4-phenyl-1H-imidazol-5-yl)methyl alcohol and 3 g of activated manganese dioxide. The obtained mixture was treated at 80° C. for 30 minutes to conduct a reaction. The reaction mixture was passed through a hot filter and the filter cake was washed with acetone. The washings and the filtrate were combined and concentrated to give 0.7 g of the title compound.

後処理

  1. additionThe obtained mixture was treated at 80° C. for 30 minutes
  2. customa reaction
  3. filtrationa hot filter
  4. washthe filter cake was washed with acetone
  5. concentrationconcentrated

出典と根拠

ORDレコード
ord-1d0ccdf2d34941c5830bb3da0c7a2c75
出典データセット
uspto-grants-1996_07
特許番号
US05541213

反応ノート

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