2-Chloro-6-methylaniline → HCID 21836027、化合物

HRID 1739624ノート

反応式

HRID 1739624 の反応式
[F:1][C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[C:7](=[O:17])[C:6]=2[C:5]([F:18])=[C:4](F)[C:3]=1[F:20].[Cl:21][C:22]1[CH:28]=[CH:27][CH:26]=[C:25]([CH3:29])[C:23]=1[NH2:24]>>[Cl:21][C:22]1[CH:28]=[CH:27][CH:26]=[C:25]([CH3:29])[C:23]=1[NH:24][C:4]1[C:3]([F:20])=[C:2]([F:1])[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[C:7](=[O:17])[C:6]=2[C:5]=1[F:18].[Cl:21][C:22]1[CH:28]=[CH:27][CH:26]=[C:25]([CH3:29])[C:23]=1[NH:24][C:4]1[C:3]([NH:24][C:23]2[C:25]([CH3:29])=[CH:26][CH:27]=[CH:28][C:22]=2[Cl:21])=[C:2]([F:1])[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[C:7](=[O:17])[C:6]=2[C:5]=1[F:18]

参加物

4

反応物 2

HCID 68972-Chloro-6-methylaniline2 回HCID 2833793HCID 2833793、化合物

生成物 2

HCID 21836027HCID 21836027、化合物HCID 21836034HCID 21836034、化合物

実験手順

2 g of 1,2,3,4-Tetrafluoroanthraquinone and 25 g of 2-chloro-6-methylaniline were charged in a 50 cc, four necked flask and then the reaction was carried out at 140° C. for about 6 hours. After completion of reaction, 2-chloro-6-methylaniline was distilled out from the reaction solution and a column purification thereof was effected to give rise to 1.07 g of 2-(2-chloro-6-methylanilino)-1,3,4-trifluoroanthraquinone (Dye 8') yield 37.3 mol %) and 0.78 g of 2,3-bis(2-chloro-6-methylanilino)-1,4-difluoroanthraquinone (Dye 21') (yield 24.2 mol %). The physical properties of Dye 8' and analytical values defining the compound are tabulated in Table 22 and the physical properties of Dye 21' and analytical values defining the compound are tabulated in Table 24.

後処理

  1. distillationwas distilled out from the reaction solution
  2. customa column purification

出典と根拠

ORDレコード
ord-5f957c9ab9a8433fb3c0b800ba076677
出典データセット
uspto-grants-1999_10
特許番号
US05968688

反応ノート

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