Methanol → HCID 85711141、化合物

HRID 1740344ノート

反応式

HRID 1740344 の反応式
[CH2:1]([N:9]([CH3:18])[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[Br:19][CH2:20][CH2:21][CH2:22][Cl:23].CO.C(C(C)=O)C>CCCCCC>[Br-:19].[Cl:23][CH2:22][CH2:21][CH2:20][N+:9]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8])([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[CH3:18]

参加物

6

反応物 4

HCID 887MethanolHCID 6569Methyl Ethyl KetoneHCID 80061-Bromo-3-chloropropaneHCID 78202N-Methyl-N-octyl-1-octanamine

生成物 1

HCID 85711141HCID 85711141、化合物

試薬・触媒・溶媒 1

HCID 8058Hexane溶媒

反応条件

温度
65 °C

実験手順

A one-liter, 3-necked, round-bottomed flask equipped with air condensers and a magnetic stirring plate was charged with N,N-dioctylmethylamine (202.48 grams, 0.79 moles), 1-bromo-3-chloropropane (124.8 grams, 0.79 moles) and methanol (250 mL). Reaction was maintained at 65° C. for two days. Methanol was removed by rotary evaporation under reduced pressure to yield an oil. To the oil was added ethylmethylketone (50 mL) and hexane (200 mL) causing a white solid to slowly form. The solvent was decanted from the mixture. The remaining solid was washed with hexane (50 mL) two times. The solid was placed in a vacuum oven at 35° C. for 24 hours. Yield 259 grams of a waxy solid (0.625 moles, 79%).

後処理

  1. customA one-liter, 3-necked, round-bottomed flask equipped with air condensers
  2. customReaction
  3. customMethanol was removed by rotary evaporation under reduced pressure
  4. customto yield an oil
  5. customto slowly form
  6. customThe solvent was decanted from the mixture
  7. washThe remaining solid was washed with hexane (50 mL) two times

出典と根拠

ORDレコード
ord-9d1cb1acd44e468aa5024bfcc16441a8
出典データセット
uspto-grants-1999_10
特許番号
US05969090

反応ノート

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