1,4-Dioxane hydrochloride → HCID 21838655、化合物
反応式
C([N:3]1[CH2:8][CH2:7][N:6]([CH2:9][CH2:10][O:11][CH3:12])[CH2:5][CH2:4]1)=O.[ClH:13].O1CCOCC1>CO>[ClH:13].[ClH:13].[CH3:12][O:11][CH2:10][CH2:9][N:6]1[CH2:7][CH2:8][NH:3][CH2:4][CH2:5]1参加物
4
実験手順
To a solution of 57.2 g of 1-formyl-4-methoxyethylpiperazine in 100 mL of methanol was added dropwise 180 mL of 4N-hydrochloric acid/1,4-dioxane over 1.5 hours. The mixture was stirred at room temperature for 1 hour, and the resulting crystals were filtered, washed with isopropyl ether and dried in vacuo to give 68.8 g of the title compound.
後処理
- filtrationthe resulting crystals were filtered
- washwashed with isopropyl ether
- customdried in vacuo
出典と根拠
- ORDレコード
- ord-0266294c143243be8e76115d5cdfc74c
- 出典データセット
- uspto-grants-1999_10
- 特許番号
- US05969138
反応ノート
読み込み中…