Phosphorus tribromide → 1-(Bromomethyl)-4-methoxycyclohexane

HRID 1740703

反応式

HRID 1740703 の反応式
[CH3:1][O:2][CH:3]1[CH2:8][CH2:7][CH:6]([CH2:9]O)[CH2:5][CH2:4]1.P(Br)(Br)[Br:12]>C(Cl)(Cl)(Cl)Cl>[Br:12][CH2:9][CH:6]1[CH2:7][CH2:8][CH:3]([O:2][CH3:1])[CH2:4][CH2:5]1

参加物

4

反応物 2

HCID 24614Phosphorus tribromideHCID 18533153(4-Methoxycyclohexyl)methanol

生成物 1

HCID 217065291-(Bromomethyl)-4-methoxycyclohexane

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

4-Methoxycyclohexylmethanol (10.5 g) was dissolved in carbon tetrachloride (45 g) and cooled with ice. Phosphorus tribromide (2.8 ml) was added dropwise to the above solution and stirred at ambient temperature overnight. The carbon tetrachloride layer was decanted and dried over magnesium sulfate. After filtering, the carbon tetrachloride from the filtrate was evaporated to yield pale yellow colored liquid of bromomethyl-4-methoxycyclohexane.

後処理

  1. temperaturecooled with ice
  2. customThe carbon tetrachloride layer was decanted
  3. dry with materialdried over magnesium sulfate
  4. filtrationAfter filtering
  5. customthe carbon tetrachloride from the filtrate was evaporated

出典と根拠

ORDレコード
ord-1090d29d562a414b84259e233b957a84
出典データセット
uspto-grants-1999_10
特許番号
US05972552

関連ノート

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