Ethanol → Ethyl 16-hydroxyhexadecanoate
反応式
[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([OH:19])=[O:18].S(=O)(=O)(O)O.[CH2:25](O)[CH3:26]>>[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([O:19][CH2:25][CH3:26])=[O:18]参加物
4
実験手順
To a solution of 5.0 g of 16-hydroxyhexadecanoic acid in 100 ml of ethanol was added 0.2 ml of sulfuric acid and the mixture was heated under reflux for one hour. The reaction solution was distilled off under reduced pressure. The residue was diluted with ethyl acetate and washed successively with water, a saturated aqueous solution of sodium hydrogen carbonate and a saturated aqueous solution of sodium chloride, dried over anhydrous sodium sulfate and then distilled under reduced pressure to afford the title compound.
後処理
- temperaturethe mixture was heated
- temperatureunder reflux for one hour