HCID 21834430、化合物 → HCID 21834422、化合物
反応式
[CH3:1][C:2]1[C:7]([C:8]#[C:9][CH2:10][CH2:11][CH3:12])=[CH:6][N:5]=[C:4]([NH:13][C:14](=[O:19])[C:15]([CH3:18])([CH3:17])[CH3:16])[CH:3]=1>C(OCC)(=O)C.[Pt]=O>[CH3:1][C:2]1[C:7]([CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])=[CH:6][N:5]=[C:4]([NH:13][C:14](=[O:19])[C:15]([CH3:18])([CH3:17])[CH3:16])[CH:3]=1参加物
4
実験手順
A solution of 4-methyl-2-(trimethylacetyl)amino-5-(1-pentynyl)-pyridine (225 mg, 0.87 mmol) in ethyl acetate (4.5 mL) containing platinum oxide (45 mg) was hydrogenated at atmospheric pressure for 1.5 h. The catalyst was removed by filtration through a Millex-HV 0.45 um Filter Unit. Evaporation of the filtrate gave the title compound.
後処理
- customThe catalyst was removed by filtration through a Millex-HV 0.45 um
- filtrationFilter Unit
- customEvaporation of the filtrate
出典と根拠
- ORDレコード
- ord-fd33297981394917b02fba0ec53daf36
- 出典データセット
- uspto-grants-1999_10
- 特許番号
- US05972975
反応ノート
読み込み中…