Isopropyl iodide → 4-Methyl-6-(2-methylpropyl)-2-(2,5-dimethylpyrrol-1-yl)pyridine

HRID 1740984

反応式

HRID 1740984 の反応式
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([N:9]2[C:13]([CH3:14])=[CH:12][CH:11]=[C:10]2[CH3:15])[CH:3]=1.I[CH:17]([CH3:19])[CH3:18]>>[CH3:1][C:2]1[CH:7]=[C:6]([CH2:8][CH:17]([CH3:19])[CH3:18])[N:5]=[C:4]([N:9]2[C:13]([CH3:14])=[CH:12][CH:11]=[C:10]2[CH3:15])[CH:3]=1

参加物

3

反応物 2

HCID 6362Isopropyl iodideHCID 224907362-(2,5-Dimethyl-1H-pyrrol-1-yl)-4,6-dimethylpyridine

生成物 1

HCID 218344234-Methyl-6-(2-methylpropyl)-2-(2,5-dimethylpyrrol-1-yl)pyridine

実験手順

By analogy to Example 71, Step A, the anion of 4,6-dimethyl-2-(2,5-dimethylpyrrol-1-yl)pyridine was alkylated with 2-iodopropane to give 4-methyl-6-(2-methylpropyl)-2-(2,5-dimethylpyrrol-1-yl)pyridine.

出典と根拠

ORDレコード
ord-b6e44edf110c4c67b4640b68d7d33679
出典データセット
uspto-grants-1999_10
特許番号
US05972975

関連ノート

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