Sodium Cyanide → 2-Phenylbut-3-enenitrile
反応式
[CH:1]([CH:3](Cl)[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)=[CH2:2].[C-:11]#[N:12].[Na+]>CO.O>[CH:1]([CH:3]([C:11]#[N:12])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)=[CH2:2]参加物
4
実験手順
12.2 g of commercially available vinylbenzyl chloride (a mixture of 60% of a meta-isomer and 40% of a para-isomer) were reacted with 5 g of NaCN in a mixed solvent of methanol/water=12.2 g/5 g at 64° C. for 12 hours. A reaction product solution was filtered, and the solvent was then distilled off, followed by distillation under reduced pressure, thereby obtaining 8.1 g of vinylbenzyl cyanide (yield 71%).
後処理
- filtrationA reaction product solution was filtered
- distillationthe solvent was then distilled off
- distillationfollowed by distillation under reduced pressure
出典と根拠
- ORDレコード
- ord-a61aa2b44e454a1e831b5e9f53cd3be7
- 出典データセット
- uspto-grants-1994_08
- 特許番号
- US05336725
反応ノート
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