関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 2-Chloroaniline | HCID 7240 | — |
| 反応物 | 3-Ethoxy-4-(2-hydroxyanilino)cyclobut-3-ene-1,2-dione | HCID 2826618 | — |
| 溶媒 | Dimethyl Sulfoxide | HCID 679 | — |
| 生成物 | 3-(2-Chloroanilino)-4-(2-hydroxyanilino)-cyclobut-3-ene-1,2-dione | HCID 9901428 | — |
反応手順
To a solution of 3-ethoxy-4-(2-hydroxyanilino)-cyclobut-3-ene-1,2-dione (50 mg, 0.21 mmol) in DMSO (1.5 mL) was added 2-chloroaniline (0.023 mL, 0.21 mmol) and reaction was stirred at 110° C. overnight. Reaction was purified on HPLC (acetonitrile:water) and product was concentrated down. Solid was dried in vacuo. LC-MS (m/z) 315 (M+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07008962B2 |
|---|
| 出典データセット | uspto-grants-2006_03 |
|---|
| ORD ID | ord-32c625159c21413b8b4a064347fc92a3 |
|---|
| 出典メモ | uspto-grants-2006_03 |
|---|
