化工社化工社 化学情報印刷レポート · 研究参考用
Triethylamine → 2-Propenoic acid, 3-phenyl-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | (R)-2-Bromo-3-phenylpropionic acid | HCID 11746403 | — |
| 溶媒 | Ethyl Acetate | HCID 8857 | — |
| 生成物 | 2-Propenoic acid, 3-phenyl- | HCID 8784 | — |
反応手順
5 g of crude (2R)-2-bromo-3-phenylpropionic acid (HPLC: 92.5%) were dissolved in 20 ml of ethyl acetate and treated at room temperature with 2.7 ml of triethylamine. After a stirring time of about 150 minutes, no precipitation of the product was to be observed. An HPLC analysis of the solution showed that the (2R)-2-bromo-3-phenyl-propionic acid had reacted completely to give cinnamic acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07009047B2 |
| 出典データセット | uspto-grants-2006_03 |
| ORD ID | ord-fa8f039f982e47f59386fc1d90ea5567 |
| 出典メモ | uspto-grants-2006_03 |