Acetic Anhydride → HCID 22238064、化合物

HRID 1743385ノート

反応式

HRID 1743385 の反応式
[C:1](OC(=O)C)(=[O:3])C.[CH3:8][CH:9]1[CH2:17][C:16]2[C:11](=[C:12]([CH3:20])[C:13]([CH3:19])=[C:14]([OH:18])[CH:15]=2)[NH:10]1>C(O)=O>[OH:18][C:14]1[CH:15]=[C:16]2[C:11](=[C:12]([CH3:20])[C:13]=1[CH3:19])[N:10]([CH:1]=[O:3])[CH:9]([CH3:8])[CH2:17]2

参加物

4

反応物 2

HCID 7918Acetic AnhydrideHCID 22238098HCID 22238098、化合物

生成物 1

HCID 22238064HCID 22238064、化合物収率 49%

試薬・触媒・溶媒 1

HCID 284Formic Acid溶媒

実験手順

Acetic anhydride (0.76 mL, 8.1 mmol) was added to formic acid (4 mL), and the mixture was stirred at room temperature for 15 minutes. To this solution was added 2,3-dihydro-2,6,7-trimethyl-1H-indole-5-ol (0.71 g, 4.0 mmol), and the mixture was stirred at room temperature for 5 hours. Ice was added to the reaction mixture, and precipitated solid was filtered to obtain 0.40 g of the title compound.

後処理

  1. stirringthe mixture was stirred at room temperature for 5 hours
  2. additionIce was added to the reaction mixture
  3. customprecipitated solid
  4. filtrationwas filtered

出典と根拠

ORDレコード
ord-bbaa5d85196d44da98a1b9ee0d7f8902
出典データセット
uspto-grants-2006_03
特許番号
US07008940B1

反応ノート

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