化工社化工社 化学情報印刷レポート · 研究参考用
1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid → N-(3-Cyano-4-pyrrolidinophenyl)-1-(4-fluorophenyl)-5-methylpyrazole-4-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid | HCID 4270263 | — |
| 反応物 | 5-Amino-2-(pyrrolidin-1-yl)benzonitrile | HCID 10750087 | — |
| 生成物 | N-(3-Cyano-4-pyrrolidinophenyl)-1-(4-fluorophenyl)-5-methylpyrazole-4-carboxamide | HCID 22228145 | 48.1% |
反応手順
By the reaction and treatment in the same manner as in Example 64 using 1-(4-fluorophenyl)-5-methylpyrazole-4-carboxylic acid (1.2 g) and 5-amino-2-pyrrolidinobenzonitrile (0.8 g), the title compound (0.8 g) was obtained, melting point: 185° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07015218B1 |
| 出典データセット | uspto-grants-2006_03 |
| ORD ID | ord-3ce1e9227d354bdebcf1d1e583c5a18f |
| 出典メモ | uspto-grants-2006_03 |