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HRID 1744632作成日：2026年10月27日

1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride → 1-(4-Chlorophenyl)-N-[2-cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-5-methylpyrazole-4-carboxamide

https://huagongshe.com/reaction/1744632

反応式

関与物質

役割名称HCID仕込み量
反応物1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chlorideHCID 2776128—
反応物2-Amino-5-(4-morpholinopiperidin-1-yl)benzonitrileHCID 22227997—
生成物1-(4-Chlorophenyl)-N-[2-cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-5-methylpyrazole-4-carboxamideHCID 2222810018.3%

反応手順

By the reaction and treatment in the same manner as in Example 150 using 1-(4-chlorophenyl)-5-methylpyrazole-4-carboxylic chloride (0.81 g) and 2-amino-5-(4-morpholinopiperidin-1-yl)benzonitrile (0.9 g), the title compound (0.29 g) was obtained, melting point: 212–213° C.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07015218B1
出典データセットuspto-grants-2006_03
ORD IDord-353198af9f28463a99d3471a04a1684d
出典メモuspto-grants-2006_03