N,N,2-trimethyl-3-nitroaniline → 1-N,1-N,2-trimethylbenzene-1,3-diamine

HRID 1744865ノート

反応式

HRID 1744865 の反応式
[CH3:1][N:2]([CH3:13])[C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([N+:9]([O-])=O)[C:4]=1[CH3:12]>CO.[H][H].[Ni]>[CH3:1][N:2]([CH3:13])[C:3]1[C:4]([CH3:12])=[C:5]([CH:6]=[CH:7][CH:8]=1)[NH2:9]

参加物

5

反応物 1

HCID 22225799N,N,2-trimethyl-3-nitroaniline

生成物 1

HCID 111373411-N,1-N,2-trimethylbenzene-1,3-diamine収率 93.7%

試薬・触媒・溶媒 3

HCID 935Nickel触媒HCID 887Methanol溶媒HCID 178418361HCID 178418361、化合物溶媒

実験手順

73 g of N,N-dimethyl-2-methyl-3-nitroaniline are dissolved in 800 ml of methanol and hydrogenated at 20° C. under 5 bar of hydrogen using Raney nickel as catalyst. 57 g of 3-dimethylamino-2-methylaniline are obtained.

出典と根拠

ORDレコード
ord-faa69c8de2a34392825725852eb6bf15
出典データセット
uspto-grants-2006_03
特許番号
US07019021B2

反応ノート

読み込み中…