化工社化工社 化学情報印刷レポート · 研究参考用
N-(2-methylpropyl)cyclopentanamine → 6-[cyclopentyl(isobutyl)amino]-N-1H-indazol-5-ylpyrimidine-4-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-(2-methylpropyl)cyclopentanamine | HCID 28428761 | — |
| 反応物 | 6-chloro-N-1H-indazol-5-ylpyrimidine-4-carboxamide | HCID 59446880 | — |
| 生成物 | 6-[cyclopentyl(isobutyl)amino]-N-1H-indazol-5-ylpyrimidine-4-carboxamide | HCID 25182913 | 78% |
反応手順
Following the general method as outlined in Example 20, starting from 6-chloro-pyrimidine-4-carboxylic acid (1H-indazol-5-yl)-amide (Intermediate 16) and cyclopentyl-isobutyl-amine (Intermediate 27), the title compound was obtained as a white solid in 78% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09150519B2 |
| 出典データセット | uspto-grants-2015_10 |
| ORD ID | ord-c4b4593710104799ae61424eede9e978 |
| 出典メモ | uspto-grants-2015_10 |