HCID 76183230、化合物 → Methyl 4,4-difluoro-3-oxobutanoate
反応式
[F:1][CH:2]([F:10])[C:3]([OH:9])=[CH:4][C:5]([O:7][CH3:8])=[O:6]>CO>[F:1][CH:2]([F:10])[C:3](=[O:9])[CH2:4][C:5]([O:7][CH3:8])=[O:6]参加物
3
実験手順
The procedure of Example 4 was repeated using methanol instead of ethanol. After distillation the methyl ester was obtained as a colorless liquid. According to the 1H NMR data the product was a tautomeric mixture of ca. 60% keto form and ca. 40% enol form (methyl 4,4-difluoro-3-hydroxybut-2-enoate).
後処理
- distillationAfter distillation the methyl ester
- customwas obtained as a colorless liquid
出典と根拠
- ORDレコード
- ord-5ca2312bf468435da2dfd0d085194da8
- 出典データセット
- uspto-grants-2015_10
- 特許番号
- US09156771B2
反応ノート
読み込み中…