関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 3-(3-chloro-4-methyl-1H-pyrazol-1-yl)pyridine | HCID 21624435 | — |
| 反応物 | Sodium Permanganate | HCID 23673458 | — |
| 溶媒 | tert-Butanol | HCID 6386 | — |
| 生成物 | 3-chloro-1-(pyridin-3-yl)-1H-pyrazole-4-carboxylic acid | HCID 86705825 | — |
反応手順
In another embodiment, 3-(3-chloro-4-methyl-1H-pyrazol-1-yl)pyridine (3) is further oxidized by sodium permanganate in water and tert-butanol and heated at about 80° C. The 3-chloro-1-(pyridin-3-yl)-1H-pyrazole-4-carboxylic acid (4) can be isolated and purified by standard techniques.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US09156813B1 |
|---|
| 出典データセット | uspto-grants-2015_10 |
|---|
| ORD ID | ord-be553582a9af4426a83f30a45ebb05d8 |
|---|
| 出典メモ | uspto-grants-2015_10 |
|---|
