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HRID 1749305作成日:2026年10月27日

1-(cyclopropylmethyl)-N-methylpiperidine-4-amine → 2-(5-amino-4,6-dimethylpyrimidine-2-yloxy)-N-(1-(cyclopropylmethyl)piperidine-4-yl)-N-methylpropanamide

https://huagongshe.com/reaction/1749305

反応式

関与物質

役割名称HCID仕込み量
反応物1-(cyclopropylmethyl)-N-methylpiperidine-4-amineHCID 43314908—
反応物2-(5-(Tert-butoxycarbonylamino)-4,6-dimethylpyrimidine-2-yloxy)propanoic acidHCID 59336093—
生成物2-(5-amino-4,6-dimethylpyrimidine-2-yloxy)-N-(1-(cyclopropylmethyl)piperidine-4-yl)-N-methylpropanamideHCID 59336143—

反応手順

The title compound was synthesized from Compound 12 and 1-(cyclopropylmethyl)-N-methyl-piperidine-4-amine in the same manner as in Example 64.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09156817B2
出典データセットuspto-grants-2015_10
ORD IDord-dca826fd89bc43dab7f46580e6bb9692
出典メモuspto-grants-2015_10