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(1S,2S)-trans-N-Boc-1,2-cyclopentanediamine → N-[(1S,2S)-2-Aminocyclopentyl]-2-(2H-1,2,3-triazol-2-yl)benzamide hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (1S,2S)-trans-N-Boc-1,2-cyclopentanediamine | HCID 17040218 | — |
| 反応物 | 2-(2H-1,2,3-Triazol-2-yl)benzoic acid | HCID 21313592 | — |
| 反応物 | HCID 118308082 | HCID 118308082 | — |
| 生成物 | N-[(1S,2S)-2-Aminocyclopentyl]-2-(2H-1,2,3-triazol-2-yl)benzamide hydrochloride | HCID 118025476 | — |
反応手順
Prepared according to the procedure for N-[(1S,2S)-2-aminocyclopentyl]-2-(3-methyl-1,2,4-oxadiazol-5-yl)benzamide hydrochloride (Intermediate 2) from tert-butyl N-[(1S,2S)-2-aminocyclopentyl]carbamate (CAS number 586961-34-4; 1.58 g, 7.94 mmol) and 2-(2H-1,2,3-triazol-2-yl)benzoic acid (CAS number 1001401-62-2; 1.64 g, 8.68 mmol) to afford the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09156829B2 |
| 出典データセット | uspto-grants-2015_10 |
| ORD ID | ord-7e865f0733e64550a3e2d0cf06e0a145 |
| 出典メモ | uspto-grants-2015_10 |