Bromobenzene → 1,6-dimethyl-4-hydroxy-N-(1-methylpyrazol-3-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide

反応式

[Br:23][c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1.[CH3:1][n:2]1[c:3](=[O:15])[c:4]([C:10]([O:12][CH2:11][CH3:13])=[O:14])[c:5]([OH:9])[cH:6][c:7]1[CH3:8].[NH2:16][c:17]1[n:18][n:19]([CH3:22])[cH:20][cH:21]1>>[CH3:1][n:2]1[c:3](=[O:15])[c:4]([C:10](=[O:12])[NH:16][c:17]2[n:18][n:19]([CH3:22])[cH:20][cH:21]2)[c:5]([OH:9])[cH:6][c:7]1[CH3:8]

参加物

反応物 3

HCID 7961Bromobenzene

HCID 1372541-Methyl-3-aminopyrazole

HCID 57619607Ethyl 1,6-dimethyl-4-hydroxy-2-oxo-1,2-dihydropyridine-3-carboxylate

生成物 1

HCID 576196061,6-dimethyl-4-hydroxy-N-(1-methylpyrazol-3-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide

出典と根拠

ORDレコード: ord-40dadcd8dd654ad5baaab7c145f144b4
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…