Hydrogen iodide → 4-Iodo-6-(4-ethoxyphenyl)pyrimidine
反応式
F[C:2]1[CH:3]=[C:4](B(O)O)[CH:5]=[CH:6][C:7]=1[O:8][CH2:9][CH3:10].Cl[C:15]1[CH:20]=[C:19](Cl)[N:18]=[CH:17][N:16]=1.[IH:22]>>[I:22][C:15]1[CH:20]=[C:19]([C:4]2[CH:5]=[CH:6][C:7]([O:8][CH2:9][CH3:10])=[CH:2][CH:3]=2)[N:18]=[CH:17][N:16]=1参加物
4
実験手順
The compound was prepared according to Example 1 using 3-fluoro-4-ethoxyphenylboronic acid and 4,6-dichloropyrimidine. The resultant chloro compound was converted to iodo with hydroiodic acid as described in the general procedure.
後処理
- customThe compound was prepared
出典と根拠
- ORDレコード
- ord-06a354a8cc4c4b6b8452ec38e1ce6158
- 出典データセット
- uspto-grants-2015_10
- 特許番号
- US09162987B2
反応ノート
読み込み中…