Thiourea → HCID 178429715、化合物
反応式
[N:1]([CH2:4][C:5]1[N:15]=[C:8]2[N:9]=[C:10]([CH3:14])[CH:11]=[C:12](Cl)[N:7]2[N:6]=1)=[N+:2]=[N-:3].NC(N)=[S:18]>C(O)C>[N:1]([CH2:4][C:5]1[N:15]=[C:8]2[N:9]=[C:10]([CH3:14])[CH:11]=[C:12]([SH:18])[N:7]2[N:6]=1)=[N+:2]=[N-:3]参加物
4
実験手順
2-Azidomethyl-7-chloro-5-methyl[1.2.4]triazolo-[1,5-a]pyrimidine (2.98 g) are suspended in 70 ml of ethanol, treated with 1.1 g of thiourea and heated at reflux for 45 minutes. The reaction mixture is stirred in an ice bath for 30 minutes. The resulting precipitate is filtered off under suction and dried in a vacuum at 40° C. There are obtained 2.76 g of 2-azidomethyl-5methyl[1.2.4]triazolo[1,5-a]pyrimidine-7-thiol as yellow crystals of melting point 214°-215° C.
後処理
- temperatureheated
- temperatureat reflux for 45 minutes
- filtrationThe resulting precipitate is filtered off under suction
- customdried in a vacuum at 40° C
出典と根拠
- ORDレコード
- ord-937c5193da354e5da954000b19cd3d47
- 出典データセット
- uspto-grants-1995_08
- 特許番号
- US05438052
反応ノート
読み込み中…