Chlorine → 1-Chloro-2-(difluoromethoxy)benzene

HRID 1756278ノート

反応式

HRID 1756278 の反応式
[F:1][CH:2]([F:10])[O:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[Cl:11]Cl>FC(F)(F)C1C=CC=C(C(F)(F)F)C=1.[Cl-].[K+]>[Cl:11][C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=1[O:3][CH:2]([F:10])[F:1]

参加物

5

反応物 2

HCID 24526Chlorine2 回HCID 68015(Difluoromethoxy)benzene2 回

生成物 1

HCID 134050971-Chloro-2-(difluoromethoxy)benzene

試薬・触媒・溶媒 2

HCID 4873Potassium Chloride触媒HCID 223106Benzene, 1,3-bis(trifluoromethyl)-溶媒

実験手順

0.5 g of potassium chloride and 10 g of difluoromethoxybenzene were placed in 100 ml of 1,3-bistrifluoromethylbenzene and chlorine was then introduced at 100° C. under UV irradiation. A further 20 g of difluoromethoxybenzene were metered in over a period of 1 hour. When the chlorine uptake had ended, the mixture was purged with nitrogen and then distilled to give 35.5 g of chlorodifluoromethoxybenzene (boiling point: 144° C., refractive index nD20 : 1.4479).

後処理

  1. customwere metered in over a period of 1 hour
  2. customthe mixture was purged with nitrogen
  3. distillationdistilled

出典と根拠

ORDレコード
ord-7bcc8a3fe4fc4ac4b265c38b8f15a686
出典データセット
uspto-grants-1995_08
特許番号
US05440051

反応ノート

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