2-cyano-N-(propan-2-yl)acetamide → N-Isopropyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide

HRID 1757664

反応式

HRID 1757664 の反応式
[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]=1[OH:10])[CH:5]=O.[CH:14]([NH:17][C:18](=[O:22])[CH2:19][C:20]#[N:21])([CH3:16])[CH3:15]>>[CH:14]([NH:17][C:18](=[O:22])[C:19]([C:20]#[N:21])=[CH:5][C:4]1[CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]([OH:10])=[C:2]([OH:1])[CH:3]=1)([CH3:16])[CH3:15]

参加物

3

反応物 2

HCID 7357952-cyano-N-(propan-2-yl)acetamideHCID 57489573,4-Dihydroxy-5-nitrobenzaldehyde

生成物 1

HCID 54130688N-Isopropyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide

実験手順

The procedure described in Example 99 was repeated using 1.83 g of 3,4-dihydroxy-5-nitrobenzaldehyde and 1.3 g of N-isopropylcyanoacetamide. Yield 1.46 g (50%), m.p. 243°-245° C.

出典と根拠

ORDレコード
ord-514acbb75a7340a0b0adf568180c5a97
出典データセット
uspto-grants-1995_08
特許番号
US05446194

関連ノート

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