化工社化工社 化学情報印刷レポート · 研究参考用
Formaldehyde → Tetrahydro-N-methyl-N-(phosphonomethyl)-3-thiophenamine 1,1-dioxide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Formaldehyde | HCID 712 | — |
| 反応物 | Water | HCID 962 | — |
| 反応物 | Phosphorous acid | HCID 107909 | — |
| 反応物 | 3-(Methylamino)-1lambda6-thiolane-1,1-dione hydrochloride | HCID 2770817 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Tetrahydro-N-methyl-N-(phosphonomethyl)-3-thiophenamine 1,1-dioxide | HCID 20509047 | 86.3% |
反応手順
A mixture of N-methyltetrahydro-3-thiophenamine 1,1-dioxide hydrochloride (37.2 parts, 0.20 mole); 90 percent paraformaldehyde (6.8 parts, 0.22 mole); orthophosphorous acid (18.0 parts, 0.22 mole); and water (30 parts) was heated at its reflux temperature for 3 hours. After cooling, the solution was stirred into ethanol (150 ml.) and the sticky, white precipitate was triturated under more ethanol. After being dried in vacuo over P2O5 the product weighed 42.0 g. (86.3 percent yield). m.p. 222°-225° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04374040 |
| 出典データセット | uspto-grants-1983_02 |
| ORD ID | ord-3df3fb0889284f939f538ddcc18be3a7 |
| 出典メモ | uspto-grants-1983_02 |