Benzyl Bromide → HCID 13117017、化合物
反応式
[OH:1][C:2]1[CH:3]=[N:4][O:5][CH:6]=1.[CH2:7](Br)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.C(=O)([O-])[O-].[K+].[K+]>CC(C)=O>[CH2:7]([O:1][C:2]1[CH:3]=[N:4][O:5][CH:6]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1参加物
5
反応条件
- 温度
- 25 °C
実験手順
A mixture containing 200 mg of 4-hydroxyisoxazole in 10 ml of acetone together with 1.5 equivalents of benzyl bromide and 1.5 equivalents of potassium carbonate is stirred at about 25° C. for five hours. The solid is filtered and the filtrate concentrated to an oil. The crude material is purified by chromatography on silica gel.
後処理
- filtrationThe solid is filtered
- concentrationthe filtrate concentrated to an oil
- customThe crude material is purified by chromatography on silica gel
出典と根拠
- ORDレコード
- ord-8b06d7e984b2497ea462637c04ad794f
- 出典データセット
- uspto-grants-1982_07
- 特許番号
- US04339588
反応ノート
読み込み中…