Sulfuric Acid → HCID 13035411、化合物
反応式
[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH2:9][CH:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[NH:7]C1=O.S(=O)(=O)(O)O>O.[OH-].[K+]>[NH2:7][CH:8]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[CH2:9][NH:5][CH2:4][CH2:3][O:2][CH3:1]参加物
5
実験手順
The racemic 1-(2-methoxyethyl)-4-phenyl-2-imidazolidone (2.2 g) obtained is heated at 140°-150° C. for 20 hours with 60 weight percent sulfuric acid. The solution is cooed to room temperature, diluted with water and 20% potassium hydroxide to attain a pH of 10 and extracted with methylene chloride. The extracts are washed, dried and concentrated to yield racemic N-(2-amino-2-phenylethyl)-2-methoxyethylamine, [α]D20 =-0.00 (c=1, CHCl3).
後処理
- customis cooed to room temperature
- extractionextracted with methylene chloride
- washThe extracts are washed
- customdried
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-537e0058bdcb4a4aa77d984b6860fbae
- 出典データセット
- uspto-grants-1982_07
- 特許番号
- US04339603
反応ノート
読み込み中…