4-Fluorobenzaldehyde → Benzenamine, N-[(4-fluorophenyl)methylene]-4-(methylsulfonyl)-
反応式
[CH3:1][S:2]([C:5]1[CH:11]=[CH:10][C:8]([NH2:9])=[CH:7][CH:6]=1)(=[O:4])=[O:3].[F:12][C:13]1[CH:20]=[CH:19][C:16]([CH:17]=O)=[CH:15][CH:14]=1>C1(C)C=CC=CC=1>[F:12][C:13]1[CH:20]=[CH:19][C:16]([CH:17]=[N:9][C:8]2[CH:10]=[CH:11][C:5]([S:2]([CH3:1])(=[O:3])=[O:4])=[CH:6][CH:7]=2)=[CH:15][CH:14]=1参加物
4
実験手順
A mixture of 19.60 g (115 mmol) of 4-methylsulfonylaniline, 12.19 mL (115 mmol) of 4-fluorobenzaldehyde and 590 mL of toluene was refluxed in a Dean-Stark for 2 days. The solvent was removed and the crude product obtained was directly used in the next reaction.
後処理
- temperaturewas refluxed in a Dean-Stark for 2 days
- customThe solvent was removed
出典と根拠
- ORDレコード
- ord-a20ef69699cf4e3296d198b4a78421e2
- 出典データセット
- uspto-grants-2005_01
- 特許番号
- US06838476B1
反応ノート
読み込み中…