Tetramethoxypropane → 2-Amino-4-chloro-pyrido[2,3-d]pyrimidine
反応式
[NH2:1][C:2]1[N:7]=[C:6]([Cl:8])[CH:5]=[C:4]([NH2:9])[N:3]=1.CO[CH:12](OC)[CH2:13][CH:14](OC)OC>>[NH2:1][C:2]1[N:7]=[C:6]([Cl:8])[C:5]2[CH:14]=[CH:13][CH:12]=[N:9][C:4]=2[N:3]=1参加物
3
実験手順
Starting from 2,6-diamino-4-chloropyrimidine and 1,1,3,3-tetramethoxypropane and using a procedure analogous to that of Example 71, the above compound is isolated after chromatographic purification on silica gel with methanol/diisopropylether (1:1) as a yellow oil which can be used in the following reactions without any further purification.
後処理
- customthe above compound is isolated
- customafter chromatographic purification on silica gel with methanol/diisopropylether (1:1) as a yellow oil which
- customcan be used in the following reactions without any further purification
出典と根拠
- ORDレコード
- ord-64b68a6731894e339d2dfaf406409927
- 出典データセット
- uspto-grants-1989_05
- 特許番号
- US04826528
反応ノート
読み込み中…