Ammonia → HCID 10997097、化合物
反応式
[CH2:1]([N:4]([C:10]([O:12]C)=O)[CH2:5][C:6](OC)=[O:7])[C:2]#[CH:3].[NH3:14]>>[CH2:1]([N:4]1[CH2:5][C:6](=[O:7])[NH:14][C:10]1=[O:12])[C:2]#[CH:3]参加物
3
実験手順
3.0 g of methyl N-propargyl-N-methoxycarbonylglycinate were dissolved in 40 ml of 28% aqueous ammonia. Then the mixture was maintained under the pressure of 10-13 kg/cm2 at 100°-110° C. for an hour. Then the solvent was evaporated off from the reaction mixture. The resulting mixture was subjected to a column chromatography on silica gel (5:1 ethyl acetate:methanol as eluent) to obtain 0.65 g of 1-propargyl-2,4-dioxoimidazolidine.
後処理
- temperatureThen the mixture was maintained under the pressure of 10-13 kg/cm2 at 100°-110° C. for an hour
- customThen the solvent was evaporated off from the reaction mixture
出典と根拠
- ORDレコード
- ord-4f522af51f2d43db858a99d16f8429f9
- 出典データセット
- uspto-grants-1989_05
- 特許番号
- US04827020
反応ノート
読み込み中…