4-(Dimethylamino)Benzaldehyde → 1-[[p-(Dimethylamino)benzylidene]amino]-2-ethylimidazole hydrochloride
反応式
[CH3:1][N:2]([CH3:11])[C:3]1[CH:10]=[CH:9][C:6]([CH:7]=O)=[CH:5][CH:4]=1.[ClH:12].[NH2:13][N:14]1[CH:18]=[CH:17][N:16]=[C:15]1[CH2:19][CH3:20]>C(O)(=O)C>[ClH:12].[CH3:1][N:2]([CH3:11])[C:3]1[CH:10]=[CH:9][C:6]([CH:7]=[N:13][N:14]2[CH:18]=[CH:17][N:16]=[C:15]2[CH2:19][CH3:20])=[CH:5][CH:4]=1参加物
4
実験手順
2.24 g (15 mmol) of p-dimethylaminobenzaldehyde are added to a solution of 2.22 g (15 mmol) of 1-amino-2-ethylimidazole hydrochloride in 40 ml of glacial acetic acid. After leaving to stand at room temperature for 24 hours the product is crystallized out by the addition of ether and subsequently recrystallized from ethanol/ether. There is obtained 1-[[p-(dimethylamino)benzylidene]amino]-2-ethylimidazole hydrochloride of melting point 226°-228°.