Ammonia → HCID 86743054、化合物
反応式
[ClH:1].[C:2]1([CH2:8][O:9][C:10]([NH:12][CH2:13][CH2:14][C:15]2[C:23]3[C:18](=[CH:19][CH:20]=[C:21]([C:24](=[NH:28])OCC)[CH:22]=3)[NH:17][CH:16]=2)=[O:11])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH3:29]>>[OH2:9].[ClH:1].[NH2:29][N:28]=[CH:24][C:21]1[CH:22]=[C:23]2[C:18](=[CH:19][CH:20]=1)[NH:17][CH:16]=[C:15]2[CH2:14][CH2:13][NH:12][C:10](=[O:11])[O:9][CH2:8][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1参加物
3
実験手順
A solution of the product of Stage (i) (0.1 g) in methanolic ammonia solution (25 ml) was stirred at room temperature for 72 h. The mixture was reduced to dryness and the residual oil triturated with a mixture of ethyl acetate and ethanol to give the title compound as a powder (0.06 g), m.p. 248°-250°.
後処理
- customthe residual oil triturated with a mixture of ethyl acetate and ethanol
出典と根拠
- ORDレコード
- ord-ecfba88c16ab46f99d23743a4de4432f
- 出典データセット
- uspto-grants-1989_05