7-Methoxy-1H-indole-2-carboxylic acid → 2-Methylpropyl 7-methoxy-1H-indole-2-carboxylate
反応式
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:11]=1[NH:10][C:9]([C:12]([OH:14])=[O:13])=[CH:8]2>C(O)C(C)C>[CH2:6]([O:13][C:12]([C:9]1[NH:10][C:11]2[C:7]([CH:8]=1)=[CH:6][CH:5]=[CH:4][C:3]=2[O:2][CH3:1])=[O:14])[CH:7]([CH3:11])[CH3:8]参加物
3
実験手順
Under the conditions of Example 8(A), 8 g of 7-methoxyindole-2-carboxylic acid is converted into the acid chloride and the latter is reacted with isobutanol. After working up of the reaction product and recrystallization from petroleum ether, 6.2 g of 7-methoxyindole-2-carboxylic acid isobutyl ester is obtained, mp 100°-101° C.
後処理
- customAfter working up of the reaction product and recrystallization from petroleum ether
出典と根拠
- ORDレコード
- ord-fca02b4cf1fa4da4b94b8c41a0b42ce9
- 出典データセット
- uspto-grants-1989_05
- 特許番号
- US04835175
反応ノート
読み込み中…