3-(Methylsulfanyl)propanenitrile → HCID 178458073、化合物

HRID 1762976

反応式

HRID 1762976 の反応式
CSCCC#N.C1SC(NC(N)=N)=NC=1CS[CH2:18][CH2:19][C:20]([NH:22][S:23]([NH2:26])(=[O:25])=[O:24])=[NH:21]>>[S:23]([NH:22][C:20](=[NH:21])[CH:19]=[CH2:18])(=[O:25])(=[O:24])[NH2:26]

参加物

3

反応物 2

HCID 5483863-(Methylsulfanyl)propanenitrileHCID 178418935HCID 178418935、化合物

生成物 1

HCID 178458073HCID 178458073、化合物

実験手順

N-sulfamyl-acrylamidine was prepared by a four-step procedure from 3-(methylthio)-propionitrile, with an extremely low (5.5%) yield in several days. The products of the subsequent steps, including famotidine, were isolated by column chromatography.

後処理

  1. customyield in several days
  2. customwere isolated by column chromatography

出典と根拠

ORDレコード
ord-09fcdf6f02f84672bde87c942a1f3963
出典データセット
uspto-grants-1989_05
特許番号
US04835281

関連ノート

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