HCID 20310988、化合物 → HCID 20310959、化合物
反応式
ClCCCC(OC(=O)C)CCCCCCC.BrCC=CC(OC(=O)C)CCCCC.C([O:34][CH:35]([CH2:58][CH2:59][CH2:60][CH2:61][CH2:62][CH2:63][CH3:64])[CH2:36][CH2:37][CH2:38][N:39]([CH2:44][CH2:45][CH2:46][C:47]1[CH:57]=[CH:56][C:50]([C:51]([O:53]CC)=[O:52])=[CH:49][CH:48]=1)[S:40]([CH3:43])(=[O:42])=[O:41])(=O)C>>[OH:34][CH:35]([CH2:58][CH2:59][CH2:60][CH2:61][CH2:62][CH2:63][CH3:64])[CH2:36][CH2:37][CH2:38][N:39]([CH2:44][CH2:45][CH2:46][C:47]1[CH:57]=[CH:56][C:50]([C:51]([OH:53])=[O:52])=[CH:49][CH:48]=1)[S:40]([CH3:43])(=[O:41])=[O:42]参加物
4
実験手順
This compound is prepared by the series of reactions described in Example 3, except that in Step B an equivalent amount of 1-chloro-4-acetoxyundecane is substituted for 1-bromo-4-acetoxy-2-nonene and the heating period at 90° C. is extended to 28 hours. There is thus obtained in Step B of this example, ethyl 4-{3-[N-(4-acetoxyundecyl)methanesulfonamido]propyl}benzoate. Saponficiation of this ester is STep C yields 4-{3-[N-(4-hydroxyundecyl)methanesulfonamido]propyl}benzoic acid.
後処理
- custom