Hydrochloric Acid → HCID 20308866、化合物

HRID 1763944ノート

反応式

HRID 1763944 の反応式
[NH2:1][C:2](=[O:29])[C:3]([NH:5][CH:6]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[C:7]([O:9]C(C1C=CC=CC=1)C1C=CC=CC=1)=[O:8])=[O:4].Cl>C(O)(=O)C>[NH2:1][C:2](=[O:29])[C:3]([NH:5][CH:6]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[C:7]([OH:9])=[O:8])=[O:4]

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 86736018Diphenylmethyl α-[(2-amino-2-oxoacetyl)amino]benzeneacetate

生成物 1

HCID 20308866HCID 20308866、化合物

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

13 g. of the product of Example 12 are added to 250 ml. of a 6N solution of hydrochloric acid in glacial acetic acid. After stirring for 15 minutes everything dissolves. The reaction solution is evaporated at room temperature and the white crystalline residue is triturated with ether, filtered under suction and recrystallized from water to obtain DL-α-[(2-amino-1,2-dioxoethyl)amino]phenylacetic acid as white crystals, m.p. 193°.

後処理

  1. dissolutiondissolves
  2. customThe reaction solution is evaporated at room temperature
  3. customthe white crystalline residue is triturated with ether
  4. filtrationfiltered under suction
  5. customrecrystallized from water

出典と根拠

ORDレコード
ord-000079a2dfc64037819f825beb8631fb
出典データセット
uspto-grants-1978_09
特許番号
US04113943

反応ノート

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